Prolonged-phrase animal studies have not been done to evaluate the carcinogenic opportunity of codeine or of promethazine, nor are there other animal or human information regarding carcinogenicity, mutagenicity, or impairment of fertility Using these brokers.
This medication is prescribed in your current affliction only. Tend not to use it later for one more problem Except told to take action by your medical doctor. A different medication may very well be essential in People scenarios.
In case you are prescribed this medication on a regular timetable and pass up a dose, just take it the moment you keep in mind. If it is near the time of the following dose, skip the missed dose. Consider your future dose at the normal time. Usually do not double the dose to catch up.
Retail store at place temperature far from light and humidity. Never shop in the toilet. Keep all remedies faraway from little ones and pets.
Codeine has very low plasma protein binding with about seven to twenty five% of codeine sure to plasma proteins. Codeine passes the blood Mind barrier and the placental barrier. Modest amounts of codeine and its metabolite, morphine, are transferred to human breast milk.
Speak with your care staff about naloxone and the way to get it. Naloxone can be an crisis medication used for an opioid overdose. An overdose can come about if you are taking an excessive amount of opioid. It may also occur if an opioid is taken with A few other prescription drugs or substances, like alcohol.
Ensure that individuals have an oral dosing dispenser that actions the suitable quantity in milliliters. Counsel patients regarding how to employ an oral dosing dispenser and correctly evaluate the oral suspension as prescribed.
Your mouth might get dry. Chewing sugarless gum or sucking challenging sweet and consuming lots of water might help. Get in touch with your treatment crew if the issue won't disappear or is serious.
The lowest Promethazine codeine syrup powerful dosage needs to be used, and various medication that influence respiration needs to be avoided. Get clinical support immediately inside the not likely celebration that sluggish/shallow respiration takes place. Promethazine really should not be used by kids with liver ailment (such as possible Reyes syndrome).
Give your treatment staff a list of all remedies you use. They're going to show you the amount medication to choose. Don't get much more medication than directed. Get emergency aid instantly Should you have difficulties respiration.
The results of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are advanced, demanding careful thing to consider of the effects about the dad or mum drug, codeine, and also the Lively metabolite, morphine.
Will not flush drugs down the bathroom or pour them right into a drain Unless of course instructed to do so. Correctly discard this product or service when it is expired or no more necessary. Consult your pharmacist or area waste disposal business.
Be sure you know how to get this products and what other medicines you need to steer clear of getting with it. See also Drug Interactions segment. Get health-related enable without delay if any of such extremely severe Negative effects happen: slow/shallow breathing, strange lightheadedness, extreme drowsiness/dizziness, issue waking up.
As well as its necessary consequences, a medication may possibly cause some unwanted effects. Though not every one of these Uncomfortable side effects may come about, when they do occur They could have to have clinical focus.